Is flashing the 48246S to the 52246S truly considered OC'ing?
No, technically, it should be called "unclocking". And, there is no evidence to suggest that the "6" series drives have even the slightest difference in hardware. I have yet to see one report of someone having problems with a drive at 52x that they did not also have at 48x.
I wonder how opinions will change IF LiteOn releases a new drive/firmware for 52x/32x/52x speeds, but not for 48x/32x/48x. I'll wager that many of the posters here will be flashing those 48x drives.
Form what I've been reading here, the 48125W is the pickiest Lite On drive when it comes to media.
Simply not true. Nor is this assertion born out in any of the reviews of the drives. I have the 40x, 48x, and 52x drives, all are very accepting of different media. The only problems with media are that people expect too much from it. You can't get error-free CDR's at 48x on inadequate media. In fact, my own 48125W drive is MORE accepting of marginal media than my 52246S, given that I'm burning at a reasonable speed for the media.